ADA-friendly PDF: Divide and Concquer: Using iPSC Stem Cells to Model Two Disctinct Phenotypes of X-ALD

Divide and Conquer: Using iPSC Stem Cells to Model Two Distinct phenotypes of X-ALD

X-ALD is a progressive, inherited disorder that primarily affects the adrenal cortex and nervous system white matter by promoting the accumalation of saturated, very long chain fatty acids in these tissues. Although the two primary ALD phenotypes are characterized by the same mutations in the ABCD1 gene, their clinical course is quite distinct.

More at Progressnotes, MUSC’s Medical Magazine