ADA-friendly PDF: OUT OF TUNE: Mismatch of Vascular and Neural Responses at a Fine Scale Suggests Limits of fMRI

OUT OF TUNE: Mismatch of Vascular and Neural Responses at a Fine Scale Suggests Limits of fMRI

Many brain-imaging techniques that rely on changes in the flow and oxygenation of blood including functional magnetic resonance imaging - assume that vascular changes reflect a proportional change in local neural activity. With resolution typically at about one millimeter the fRMI signal represents the blood flow averaged across many blood vessels.

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